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Hypothyroidism

HYPOTHYROIDISM it\'s clinical condition ensuing from bated current levels of T4 and /or T3 by thyroid no matter cause. once glandular disease is severe  and long standing ,it is seen as hypothyroidism that is defined by deposition of glycoprotein material(hyaluronic acid and muck polysaccharides) inflicting swelling of skin and of hypodermic tissues. 

ETIOLOGY the cause could also be primary thyroid illness or less normally illness of pituitory or hypothalamus(secondary hypothyroidism) (1)primary thyroid failure -Idiopathic atrophy of thyroid glandgland -Hasshimoto\'s thyroditis -Iodine deficiency -thyroidectomy -previous treatment with radioiodine -drug induce  like antithyroid medicine ,lithium -sunacute or silent thyroditits -agenesis of thyroid (2)Secondary thyroid failure -pituitary pathology -hypothalamic pathology CLINICAL options -Insidious in onset with physical,mental and  metabolic processes below traditional -tiredness -weight gain -cold intolerance-goiter -course dry skin -puffiness of skin with protozoal infection flush(moon face) -myxoedema-swollen oedematous look of supraclavicular region,neck,backs of hands and feet\'s -minimal sweating -alopecia -vitiligo -Bradycardia -angina -Depression -psychosis -body aches and pain -myalgia and muscles stiffness -Delayed relaxation of reflexes -Hoarseness of voice -constipation -ascitis -anemia -Infertility -menorrhagia -impotence -growth retardation -mental retardation -delayed pubescence INVESTIGATION one. THYROID perform take a look at @Reduction in free and total T4,and rise in blood {serum|liquid body substance|bodily fluid|body fluid|humor|humour} endocrine(more than fifteen to20mu/l) indicate primary glandular disease @Elevated serum tsh with traditional T4 is termed subclinical glandular disease @Reduction in free and total T4,with endocrine level among or below traditional vary recommend secondary glandular disease a pair of.SERUM cholesterin  elevated in primary glandular disease three.ECG arrhythmia MANAGEMENT 1REPLACEMENT medical care thyroxine(t4) in dose of 100mg is effective in most patients.symptomatic improvement is seen among a pair of to three weeks of beginning treatment

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