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DRUG-INDUCED GASTROINTESTINAL DISORDERS

DRUG-INDUCED channel DISORDERS

1.GASTROINTESTINAL REFLUX sickness medication like antidepressant drug acting as anticholinergic agent leads reduction in oesophageal anatomical sphincter pressure leading to reflux. 2.SALMONELLA AND CAMPYLOBACTER rubor  NSAIDS and acid supressing agent like ranitidin ,pantaprazole,rabeprazole produces inhibition in prostaglandine synthesis leads impairment in secretion layer of abdomen.it is liable for impairment in gi defence leading to infection three.ULCERATION OF gullet AND abdomen  POtessium prepration ,cytotoxic medication and oral gold ready to directly injury channel leads ulceration four.PSUDOMEMBRANOUS rubor OR inflammation Antibiotics like Mefoxin ,used in h.pylori demolition medical care leads altratio. In traditional healthy flora of enteric tract and leads rubor and inflammation five.OESOPHAGITIS Emepromium bromide ,tetracyclinele directly injured  gullet mocosa leads OESOPHAGITI half dozen.DUODINAL STRINCTURE  NSAIDS ,bisphosphonates ,potessium chloride,quinidine ar liable for duodinal strictures in late stage.

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